Antiphospholipid Antibody Syndrome: A Review

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ANTIPHOSPHOLIPID ANTIBODY SYNDROME-A CASE OF AORTIC VALVE INSUFFICIENCY

A 31 year old woman was hospitalized for evaluation of aortic valve insufficiency and her present cardiac status. Clinical and paraclinical findings strongly suggested the presence of a collagen vascular inflammatory processprecisely, the antiphospholipid antibody syndrome (APS), with systemic lupus erythematosus as the underlying disease.

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Management of antiphospholipid antibody syndrome: a systematic review.

CONTEXT Antiphospholipid antibodies are autoantibodies directed against proteins that bind to phospholipid. Antiphospholipid antibody syndrome (APS) refers to the association between antiphospholipid antibodies and thrombosis risk or pregnancy morbidity. Patients with APS may be at increased risk of recurrent arterial or venous thrombosis or pregnancy loss. OBJECTIVE To systematically review ...

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Antiphospholipid antibody syndrome.

The 2006 International Consensus Statement on an Update of the Classification Criteria for Definite Antiphospholipid Syndrome has increased the time between the two laboratory studies required for diagnosis from 6 to 12 weeks. Antibody to beta2 glycoprotein 1 has been included as a criterion. Various non-criteria diagnostic clues such as livedo reticularis, heart valve disease, thrombocytopenia...

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Treatment of antiphospholipid antibody syndrome

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease with thrombotic predilection resulting in vascular thrombotic events and obstetric complications. Management of APS focuses on anticoagulation; however, despite the solid evidence suggesting that this is the best treatment option available, a lot of debate persists regarding the intensity and duration of anticoagulation n...

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The antiphospholipid antibody syndrome: a case report

Antiphospholipid antibody syndrome is defined by the presence of thromboembolic complications and/or pregnancy morbidity in the presence of persistently increased titers of antiphospholipid antibodies. Its clinical presentation can be diverse and any organ can be involved, with a current impact in most surgical and medical specialties. The authors present the case of a 43-year-old man who, over...

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ژورنال

عنوان ژورنال: Journal of the Royal Society of Medicine

سال: 1987

ISSN: 0141-0768,1758-1095

DOI: 10.1177/014107688708000716